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Preoperative apparent diffusion coefficient value of gastric cancer by diffusion‐weighted imaging: Correlations with postoperative TNM staging
Author(s) -
Liu Song,
Wang Hao,
Guan Wenxian,
Pan Liang,
Zhou Zhuping,
Yu Haiping,
Liu Tian,
Yang Xiaofeng,
He Jian,
Zhou Zhengyang
Publication year - 2015
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.24841
Subject(s) - medicine , effective diffusion coefficient , receiver operating characteristic , diffusion mri , lymph node , stage (stratigraphy) , cancer , radiology , nuclear medicine , magnetic resonance imaging , pathological staging , paleontology , biology
Background To determine if the apparent diffusion coefficient (ADC) values of gastric cancers on the preoperative diffusion weighted imaging (DWI) correlate with the postoperative TNMs of the lesions. Methods In a retrospective clinical study, seventy patients with gastric cancers were enrolled and each underwent a MRI before surgery. DWI was obtained with a single‐shot, echo‐planar imaging sequence in the axial plane (b values: 0 and 1000 s/mm 2 ). The mean and minimum ADC values of the gastric cancers were calculated and compared among various postoperative TNM staging. Results Both mean and minimum ADC values of the gastric cancers correlated with the postoperative T staging (r = −0.464, −0.476; both P < 0.001), N staging (r = −0.402, −0.397; P = 0.001, 0.002) and TNM staging (r = −0.446, −0.437; both P < 0.001). The areas under the receiver operating characteristic (ROC) curves for the differentiating lymph node metastasis were 0.788 for the mean ADC values ( P = 0.001) and 0.778 for the minimum ADC values ( P = 0.001). Conclusion The preoperative ADC values of gastric cancers can help to assess the postoperative TNM staging. J. Magn. Reson. Imaging 2015;42:837–843.