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An introduction to ASL labeling techniques
Author(s) -
Wong Eric C.
Publication year - 2014
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.24565
Subject(s) - arterial spin labeling , perfusion , biomedical engineering , perfusion scanning , nuclear magnetic resonance , nuclear medicine , computer science , materials science , medicine , radiology , physics
Arterial spin labeling (ASL) methods allow for quantitative mapping of tissue perfusion in absolute units, without the use of contrast agents. In this technique, the magnetization of arterial blood water is labeled by magnetic inversion or saturation, and the delivery of labeled blood water to tissues is observed. In this review three classes of labeling methods for ASL are described and compared: continuous, pulsed, and velocity‐selective. The quantification of perfusion from ASL data is discussed, and methods for the extraction of new types of information using ASL and related techniques, such as mapping of vascular territories or venous oxygenation, are described. J. Magn. Reson. Imaging 2014;40:1–10 . © 2014 Wiley Periodicals, Inc .