Premium
Regional analysis of femoral head perfusion following displaced fractures of the femoral neck
Author(s) -
Dyke Jonathan P.,
Lazaro Lionel E.,
Hettrich Carolyn M.,
Hentel Keith D.,
Helfet David L.,
Lorich Dean G.
Publication year - 2015
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.24524
Subject(s) - medicine , quadrant (abdomen) , femoral head , femoral neck , perfusion , nuclear medicine , radiology , surgery , osteoporosis
Purpose To assess regional variations in the arterial and venous blood supply to the femoral head following displaced fracture of the femoral neck using dynamic contrast enhanced (DCE)‐MRI quadrant analysis. Materials and Methods A total of 27 subjects with displaced femoral neck fractures were enrolled in the study. Quadrant specific DCE‐MRI perfusion analysis was performed on a 1.5 Tesla MRI scanner. Simultaneous imaging of control and displaced fractured hips was done for comparison. Results Quadrant specific decreases were found in the arterial (A (0.52 versus 0.27; P = 5.7E‐13), Ak ep (1.0/min −1 versus 0.41/min −1 ; P = 1.3E‐9) and venous (k el (0.05/min −1 versus −0.02/min −1 ; P = 5.1E‐5) supply to the femoral head between control and injured sides using a two‐factor analysis of variance test. The fractional perfusion (initial area under the curve) in the supero/inferolateral quadrants was 49% min/54% min, in the supero/inferomedial quadrants was 43% min/46% min and for the total femoral head was 39% min on the fracture versus control sides. Conclusion Quadrant specific decreases in arterial and venous perfusion on the fracture side were observed when compared with control. J. Magn. Reson. Imaging 2015;41:550–554. © 2013 Wiley Periodicals, Inc .