Premium
Detection of infragenual arterial disease using non–contrast‐enhanced MR angiography in patients with diabetes
Author(s) -
Liu Xin,
Zhang Na,
Fan Zhaoyang,
Feng Fei,
Yang Qi,
Zheng Hairong,
Liu Pengcheng,
Li Debiao
Publication year - 2014
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.24477
Subject(s) - medicine , radiology , stenosis , magnetic resonance angiography , image quality , angiography , nuclear medicine , steady state free precession imaging , diagnostic accuracy , diabetes mellitus , magnetic resonance imaging , artificial intelligence , computer science , image (mathematics) , endocrinology
Purpose To evaluate the diagnostic performance of a newly developed non–contrast‐enhanced MR angiography (NCE‐MRA) technique using flow‐sensitive dephasing (FSD) prepared steady‐state free precession (SSFP) for detecting calf arterial disease in patients with diabetes. Materials and Methods Forty‐five patients with diabetes who underwent routine contrast‐enhanced MR angiography (CE‐MRA) of lower extremities were recruited for NCE‐MRA at the calf on a 1.5 Tesla MR system. Image quality evaluated on a 4‐point scale and diagnostic performance for detecting more than 50% arterial stenosis were statistically analyzed, using CE‐MRA as the standard of reference. Results A total of 264 calf arterial segments were obtained in the 45 patients with 88 legs. The percentage of diagnostic arterial segments was all 98% for NCE‐ and CE‐MRA. The image quality, SNR, CNR was 3.3, 177, 138, and 3.5, 103, 99, for NCE‐MRA and CE‐MRA, respectively. The average sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of NCE‐MRA were 97%, 96%, 90%, 99%, and 96%, respectively on a per‐segment basis and 90%, 84%, 82%, 91%, and 87%, respectively, on a per‐patients basis. Conclusion The NCE‐MRA technique demonstrates adequate image quality in the delineation of calf arteries and consistent diagnostic performance for detecting significant stenosis with CE‐MRA in patients with diabetes. J. Magn. Reson. Imaging 2014;40:1422–1429 . © 2013 Wiley Periodicals, Inc .