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MRI of Hepatic Epithelioid Hemangioendothelioma (HEH)
Author(s) -
Paolantonio Pasquale,
Laghi Andrea,
Vanzulli Angelo,
Grazioli Luigi,
Morana Gianni,
Ragozzino Alfonso,
Colagrande Stefano
Publication year - 2014
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.24391
Subject(s) - epithelioid hemangioendothelioma , hemangioendothelioma , medicine , pathology , radiology , immunohistochemistry
Purpose To investigate magnetic resonance imaging (MRI) characteristics of hepatic epithelioid hemangionendothelioma (HEH). Materials and Methods The study was exempted from formal Ethics Committee approval due to its retrospective and noninvasive nature. Eleven patients with histology‐proven HEH were collected from six different institutions in a 5‐year time period. In all patients a contrast‐enhanced MR study was available. Two experienced reviewers in consensus retrospectively noted potential MR findings of HEH. Reviewers separately analyzed morphological findings, tumor signal intensity, HEH contrast enhancement pattern, and tumor appearance on hepatobiliary phase and diffusion‐weighted imaging (DWI). The frequency of various findings was calculated. Results The most frequent presentation was a peripheral distribution of the lesions (72.7%), target appearance on T2‐weighted images (63.6%), low signal intensity on T1‐weighted images (63.6%), ring or target‐like enhancement at dynamic study (63.6%), and coalescence of nodules and capsular retraction (45.4%). Lack of hepatobiliary enhancement (5/8 patients) or “entrapment” hepatobiliary enhancement (3/8 patients) as well as target appearance at DWI (5/6 patients) was also observed in our series. Conclusion Although quite variable imaging appearances were seen, a target appearance on the T2‐weighted image, ring or target enhancement at dynamic study, lack of enhancement or “entrapment” at hepatobiliary phase, and target appearance on DWI are frequent findings of HEH. J. Magn. Reson. Imaging 2014;40:552–558 . © 2013 Wiley Periodicals, Inc .