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Intracranial hemangiopericytoma: MR imaging findings and diagnostic usefulness of minimum ADC values
Author(s) -
Liu Gang,
Chen ZhiYe,
Ma Lin,
Lou Xin,
Li ShiJun,
Wang YuLin
Publication year - 2013
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.24075
Subject(s) - meningioma , hemangiopericytoma , medicine , magnetic resonance imaging , diffusion mri , nuclear medicine , differential diagnosis , hyperintensity , radiology , effective diffusion coefficient , cutoff , pathology , physics , quantum mechanics
Purpose To describe the clinical and magnetic resonance (MR) imaging features of primary intracranial hemangiopericytoma (HPC), and to assess the usefulness of minimum apparent diffusion coefficient (MinADC) value of HPC in the differential diagnosis from meningioma. Materials and Methods From 2004 to 2010, fifteen patients with primary intracranial HPC were included. The clinical data, conventional MR findings (n = 15), and diffusion weighted image (DWI) features (n = 10) were retrospectively analyzed. MinADC value of the HPCs (n = 10) was measured on ADC map and was compared with that of meningiomas (n = 37). Results In 15 cases of HPC, isointense signal was detected on both T1‐weighted images (T1WI) and T2‐weighted images (T2WI) in 11 cases, and heterogeneous signal was demonstrated in 4 cases. Isointensity (n = 9) and iso‐ and slight hyperintensity (n = 1) were shown on DWI. The mean MinADC value of HPC [(1.116 ± 0.127) × 10 −3 mm 2 /s] was significantly higher than that of meningioma [(0.875 ± 0.104) × 10 −3 mm 2 /s] ( P < 0.01). For the differentiation between HPC and meningioma, the critical cutoff MinADC value was 0.991 × 10 −3 mm 2 /s, which provided the best combination of sensitivity (88.9%) and specificity (82.4%). Conclusion MinADC value may be an useful tool for the differentiation between HPC and meningioma. J. Magn. Reson. Imaging 2013;38:1146–1151. © 2013 Wiley Periodicals, Inc.