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Pulmonary perfusion MRI using interleaved variable density sampling and HighlY constrained cartesian reconstruction (HYCR)
Author(s) -
Wang Kang,
Schiebler Mark L.,
Francois Christopher J.,
Del Rio A. Munoz,
Cornejo Ma. Daniela,
Bell Laura C.,
Korosec Frank R.,
Brittain Jean H.,
Holmes James H.,
Nagle Scott K.
Publication year - 2013
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.24018
Subject(s) - medicine , perfusion , radiology , nuclear medicine , temporal resolution , sampling (signal processing) , perfusion scanning , magnetic resonance imaging , computer science , physics , filter (signal processing) , quantum mechanics , computer vision
Purpose: To demonstrate the feasibility of performing single breathhold, noncardiac gated, ultrafast, high spatial‐temporal resolution whole chest MR pulmonary perfusion imaging in humans. Materials and Methods: Eight subjects (five male, three female) were scanned with the proposed method on a 3 Tesla clinical scanner using a 32‐channel phased‐array coil. Seven (88%) were healthy volunteers, and one was a patient volunteer with sarcoidosis. The peak lung enhancement phase for each subject was scored for gravitational effect, peak parenchymal enhancement and severity of artifacts by three cardiothoracic radiologists independently. Results: All studies were successfully performed by MR technologists without any additional training. Mean parenchymal signal was very good, measuring 0.78 ± 0.13 (continuous scale, 0 = “none” → 1 = “excellent”). Mean level of motion artifacts was low, measuring 0.13 ± 0.08 (continuous scale, 0 = “none” → 1 = “severe”). Conclusion: It is feasible to perform single breathhold, noncardiac gated, ultrafast, high spatial‐temporal resolution whole chest MR pulmonary perfusion imaging in humans. J. Magn. Reson. Imaging 2013;38:751–756. © 2013 Wiley Periodicals, Inc.