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Use of conventional MR imaging and diffusion‐weighted imaging for evaluating the risk grade of gastrointestinal stromal tumors
Author(s) -
Zhou Hai Ying,
Zhang Xiao Ming,
Zeng Nan Lin,
Jian Shun Hai,
Tang Wei
Publication year - 2012
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.23784
Subject(s) - medicine , effective diffusion coefficient , diffusion mri , radiology , nuclear medicine , magnetic resonance imaging , stromal cell
Purpose: To study the risk grade of gastrointestinal stromal tumors (GISTs) with conventional MR imaging and diffusion‐weighted imaging (DWI). Materials and Methods: The abdominal MR images with DWI of 23 patients with pathologically proven GISTs during January 2010 to May 2011 were retrospectively reviewed. The conventional MR imaging findings and apparent diffusion coefficient (ADC) values of the tumors related to the risk grade were analyzed. Results: In the 23 patients, there were 13 patients with high‐risk, 5 with medium‐risk, 5 with low‐risk, and 0 with very low‐risk GISTs. Most of the conventional MR findings of the tumors did not correlate with the risk grade. The only exception to this was the correlation between risk grade and the enhancement degree of the tumor after Gd‐DTPA. The ADC values were, respectively, (1.04 ± 0.13) × 10 −3 mm 2 ·s −1 , (1.59 ± 0.06) × 10 −3 mm 2 ·s −1 and (1.94 ± 0.08) × 10 −3 mm 2 ·s −1 ( P < 0.05) in the high‐, medium‐, and low‐risk grade groups. The ADC values of GISTs decreased with the increase of the risk grade of the tumors (r = −0.957; P < 0.05). Conclusion: DWI can be used to assess the risk grade of GISTs, but conventional MR imaging is of limited use. J. Magn. Reson. Imaging 2012; 36:1395–1401. © 2012 Wiley Periodicals, Inc.