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Evaluation of sampling density on the accuracy of aortic pulse wave velocity from velocity‐encoded MRI in patients with Marfan syndrome
Author(s) -
Kröner Eleanore S.J.,
van der Geest Rob J.,
Scholte Arthur J.H.A.,
Kroft Lucia J.M.,
van den Boogaard Pieter J.,
Hendriksen Dennis,
Lamb Hildo J.,
Siebelink HansMarc J.,
Mulder Barbara J.M.,
Groenink Maarten,
Radonic Teodora,
HilhorstHofstee Yvonne,
Bax Jeroen J.,
van der Wall Ernst E.,
de Roos Albert,
Reiber Johan H.C.,
Westenberg Jos J.M.
Publication year - 2012
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.23729
Subject(s) - pulse wave velocity , marfan syndrome , medicine , sampling (signal processing) , radiology , pulse (music) , wave velocity , cardiology , materials science , physics , blood pressure , optics , composite material , detector , shear (geology)
Purpose: To evaluate the effect of spatial (ie, number of sampling locations along the aorta) and temporal sampling density on aortic pulse wave velocity (PWV) assessment from velocity‐encoded MRI in patients with Marfan syndrome (MFS). Materials and Methods: Twenty‐three MFS patients (12 men, mean age 36 ± 14 years) were included. Three PWV‐methods were evaluated: 1) reference PWV i.p. from in‐plane velocity‐encoded MRI with dense temporal and spatial sampling; 2) conventional PWV t.p. from through‐plane velocity‐encoded MRI with dense temporal but sparse spatial sampling at three aortic locations; 3) EPI‐accelerated PWV t.p. with sparse temporal but improved spatial sampling at five aortic locations with acceleration by echo‐planar imaging (EPI). Results: Despite inferior temporal resolution, EPI‐accelerated PWV t.p. showed stronger correlation ( r = 0.92 vs. r = 0.65, P = 0.03) with reference PWV i.p. in the total aorta, with less error (8% vs. 16%) and variation (11% vs. 27%) as compared to conventional PWV t.p. . In the aortic arch, correlation was comparable for both EPI‐accelerated and conventional PWV t.p. with reference PWV i.p. ( r = 0.66 vs. r = 0.67, P = 0.46), albeit 92% scan‐time reduction by EPI‐acceleration. Conclusion: Improving spatial sampling density by adding two acquisition planes along the aorta results in more accurate PWV assessment, even when temporal resolution decreases. For regional PWV assessment in the aortic arch, EPI‐accelerated and conventional PWV assessment are comparably accurate. Scan‐time reduction makes EPI‐accelerated PWV assessment the preferred method of choice. J. Magn. Reson. Imaging 2012; 36:1470–1476. © 2012 Wiley Periodicals, Inc.