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Four‐dimensional phase contrast MRI with accelerated dual velocity encoding
Author(s) -
Nett Elizabeth J.,
Johnson Kevin M.,
Frydrychowicz Alex,
Del Rio Alejandro Munoz,
Schrauben Eric,
Francois Christopher J.,
Wieben Oliver
Publication year - 2012
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.23588
Subject(s) - phase contrast microscopy , contrast (vision) , encoding (memory) , phase (matter) , medicine , computer science , radiology , nuclear medicine , physics , artificial intelligence , optics , quantum mechanics
Abstract Purpose: To validate a novel approach for accelerated four‐dimensional phase contrast MR imaging (4D PC‐MRI) with an extended range of velocity sensitivity. Materials and Methods: 4D PC‐MRI data were acquired with a radially undersampled trajectory (PC‐VIPR). A dual V enc (dV enc ) processing algorithm was implemented to investigate the potential for scan time savings while providing an improved velocity‐to‐noise ratio. Flow and velocity measurements were compared with a flow pump, conventional 2D PC MR, and single V enc 4D PC‐MRI in the chest of 10 volunteers. Results: Phantom measurements showed excellent agreement between accelerated dV enc 4D PC‐MRI and the pump flow rate (R 2 ≥ 0.97) with a three‐fold increase in measured velocity‐to‐noise ratio (VNR) and a 5% increase in scan time. In volunteers, reasonable agreement was found when combining 100% of data acquired with V enc = 80 cm/s and 25% of the high V enc data, providing the VNR of a 80 cm/s acquisition with a wider velocity range of 160 cm/s at the expense of a 25% longer scan. Conclusion: Accelerated dual V enc 4D PC‐MRI was demonstrated in vitro and in vivo. This acquisition scheme is well suited for vascular territories with wide ranges of flow velocities such as congenital heart disease, the hepatic vasculature, and others. J. Magn. Reson. Imaging 2012;35:1462–1471. © 2012 Wiley Periodicals, Inc.