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Predictive value of MRI in the localization, staging, volume estimation, assessment of aggressiveness, and guidance of radiotherapy and biopsies in prostate cancer
Author(s) -
Yakar Derya,
Debats Oscar A.,
Bomers Joyce G.R.,
Schouten Martijn G.,
Vos Pieter C.,
van Lin Emile,
Fütterer Jurgen J.,
Barentsz Jelle O.
Publication year - 2012
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.22790
Subject(s) - medicine , multiparametric mri , magnetic resonance imaging , prostate cancer , radiation therapy , radiology , prostate , stage (stratigraphy) , cancer , medical physics , paleontology , biology
Multiparametric magnetic resonance imaging (MRI) has the potential of being the ideal prostate cancer (PCa) assessment tool. Information gathered with multiparametric MRI can serve therapy choice, guidance of interventions, and treatments. The purpose of this review is to discuss the potential role of multiparametric MRI in focal therapy with respect to patient selection and directing (robot‐guided) biopsies and intensity‐modulated radiation therapy (IMRT). Multiparametric MRI is a versatile and promising technique. It appears to be the best available imaging technique at the moment in localizing, staging (primary as well as recurrent disease, and local as well as distant disease), determining aggressiveness, and volume of PCa. However, larger study populations in multicenter settings have to confirm these promising results. However, before such studies can be performed more research is needed in order to achieve standardized imaging protocols. J. Magn. Reson. Imaging 2012;35:20‐31. © 2011 Wiley Periodicals, Inc.