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Signal‐to‐noise ratio enhancement of intermolecular double‐quantum coherence MR spectroscopy in inhomogeneous fields with phased array coils on a 3 tesla whole‐body scanner
Author(s) -
Lin Yanqin,
Chen Zhong,
Zhong Jianhui
Publication year - 2011
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.22434
Subject(s) - scanner , imaging phantom , physics , phased array , coherence (philosophical gambling strategy) , electromagnetic coil , optics , signal to noise ratio (imaging) , nuclear magnetic resonance , signal (programming language) , computer science , telecommunications , quantum mechanics , antenna (radio) , programming language
Purpose To improve signal‐to‐noise ratio (SNR) of intermolecular double‐quantum coherence (iDQC) MRS on a 3 Tesla (T) whole‐body scanner. Materials and Methods A 32‐channel phased array coil was used to acquire iDQC signal of a MRS phantom in the presence of large field inhomogeneity. The obtained individual spectra from the array elements were combined together in the time domain using a multichannel nonparametric singular value decomposition algorithm. The results were compared quantitatively with those acquired with a circularly polarized (CP) head coil. Results The achieved gain in SNR ranges from 1.63 to 2.10 relative to the CP coil, mainly depending on the relative position between the surface of the phased array coil and the voxel of acquisition. Conclusion SNR enhancement of iDQC MRS in inhomogeneous fields on a 3T whole‐body scanner is feasible with phased array coils. This can facilitate iDQC applications of high‐resolution in vivo spectroscopy in the presence of field inhomogeneity for potential disease diagnosis in humans. J. Magn. Reson. Imaging 2011;33:698–703. © 2011 Wiley‐Liss, Inc.