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Usefulness of diffusion‐weighted imaging for differentiating between desmoid tumors and malignant soft tissue tumors
Author(s) -
Oka Kiyoshi,
Yakushiji Toshitake,
Sato Hiro,
Fujimoto Toru,
Hirai Toshinori,
Yamashita Yasuyuki,
Mizuta Hiroshi
Publication year - 2011
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.22406
Subject(s) - soft tissue , medicine , effective diffusion coefficient , nuclear medicine , lesion , magnetic resonance imaging , fibromatosis , diffusion mri , radiology , pathology
Purpose To evaluate the usefulness of diffusion‐weighted imaging (DWI) for differentiating between desmoid tumors and malignant soft tissue tumors. Materials and Methods Conventional MRI and DWI were performed for 8 desmoid tumors and 74 malignant soft tissue tumors. DWI was obtained with a single‐shot echo‐planar imaging sequence using a 1.5 Tesla (T) MR imager. DW images were acquired with motion‐probing gradient pulses applied along three directions (x, y, and z axes) with three b‐factors (0, 500, and 1000 s/mm 2 ). Two observers blinded to clinical information measured three regions of interest within the solid tumor and selected a minimum apparent diffusion coefficient () in each lesion. The mean ADC of desmoid tumors was calculated and compared with that of malignant soft tissue tumors using the Mann‐Whitney U test. Results The mean ADC of desmoid tumors and malignant soft tissue tumors was 1.36 ± 0.48 × 10 −3 mm 2 /s and 0.88 ± 0.20 × 10 −3 mm 2 /s (mean ± SD), respectively. The mean ADC of the desmoid tumors was significantly higher than that of malignant soft tissue tumors ( P < 0.01 ). Conclusion DWI is considered to be useful for differentiating between desmoid tumors and malignant soft tissue tumors. In the future, further investigation in a large series is necessary. J. Magn. Reson. Imaging 2011;33:189–193. © 2010 Wiley‐Liss, Inc.