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Reversed laminar appearance of articular cartilage by T1‐weighting in 3D fat‐suppressed spoiled gradient recalled echo (SPGR) imaging
Author(s) -
Xia Yang,
Zheng Shaokuan
Publication year - 2010
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.22278
Subject(s) - cartilage , laminar flow , magnetic resonance imaging , articular cartilage , nuclear magnetic resonance , gradient echo , spin echo , fast spin echo , knee cartilage , anatomy , materials science , biomedical engineering , medicine , osteoarthritis , physics , pathology , radiology , alternative medicine , thermodynamics
Purpose: To investigate the reversed intensity pattern in the laminar appearance of articular cartilage by 3D fat‐suppressed spoiled gradient recalled echo (FS‐SPGR) imaging in magnetic resonance imaging (MRI). Materials and Methods: The 3D SPGR experiments were carried out on canine articular cartilage with an echo time (TE) of 2.12 msec, a repetition time (TR) of 60 msec, and various flip angles (5° to 80°). In addition, T1, T2, and T2* in cartilage were imaged and used to explain the laminar appearance in SPGR imaging. Results: The profiles of T2 and T2* in cartilage were similar in shape. However, the T2 values from the multigradient‐echo imaging sequence were about 1/3 of those from single spin‐echo sequences at a pixel resolution of 26 μm. While the laminar appearance of cartilage in spin‐echo imaging is caused mostly by T2‐weighting, the laminar appearance of cartilage in fast imaging (ie, short TR) at the magic angle can have a reversed intensity pattern, which is caused mostly by T1‐weighting. Conclusion: The laminar appearance of articular cartilage can have opposite intensity patterns in the deep part of the tissue, depending on whether the image is T1‐weighted or T2‐weighted. The underlying molecular structure and experimental protocols should both be considered when one examines cartilage images in MRI. J. Magn. Reson. Imaging 2010;32:733–737. © 2010 Wiley‐Liss, Inc.