Premium
Filtered deconvolution of a simulated and an in vivo phase model of the human brain
Author(s) -
Grabner Günther,
Trattnig Siegfried,
Barth Markus
Publication year - 2010
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.22246
Subject(s) - deconvolution , quantitative susceptibility mapping , kernel (algebra) , wiener deconvolution , phase (matter) , blind deconvolution , filter (signal processing) , noise (video) , computer science , artificial intelligence , mathematics , physics , algorithm , computer vision , magnetic resonance imaging , image (mathematics) , medicine , combinatorics , quantum mechanics , radiology
Purpose: To remove spatial patterns in gradient echo phase images which are caused by susceptibility differences between different tissue types using filtered deconvolution and to evaluate deconvolution effects. Materials and Methods: A realistic simulated susceptibility map of the human brain was built and used to evaluate the effects of filtered deconvolution. The simulated susceptibility map was convolved with a filter kernel representing a magnetic dipole resulting in a simulated phase map. The artificial phase map was superimposed with different noise levels and deconvolved using different deconvolution kernels. The resulting contrast‐to‐noise ratios between white and gray matter of the deconvolved data provide an estimate for an optimal deconvolution kernel for a given noise level. These results were used to deconvolve an in vivo phase model representing the average of 30 phase data sets and also individual phase data acquired at 7 Tesla. Results: The deconvolved phase model shows a better anatomical agreement with the corresponding magnitude than the original phase model (5% higher κ coefficient). Visual inspection of the deconvolved individual phase shows a more consistent delineation of blood vessels. Conclusion: Filtered deconvolution of SWI phase is possible when an appropriate filter kernel is used. This helps to improve region of interest definition as unrealistic phase patterns are removed. J. Magn. Reson. Imaging 2010;32:289–297. © 2010 Wiley‐Liss, Inc.