Ultrafast imaging: Principles, pitfalls, solutions, and applications

Ultrafast MRI refers to efficient scan techniques that use a high percentage of the scan time for data acquisition. Often, they are used to achieve short scan duration ranging from sub‐second to several seconds. Alternatively, they may form basic components of longer scans that may be more robust or have higher image quality. Several important applications use ultrafast imaging, including real‐time dynamic imaging, myocardial perfusion imaging, high‐resolution coronary imaging, functional neuroimaging, diffusion imaging, and whole‐body scanning. Over the years, echo‐planar imaging (EPI) and spiral imaging have been the main ultrafast techniques, and they will be the focus of the review. In practice, there are important challenges with these techniques, as it is easy to push imaging speed too far, resulting in images of a nondiagnostic quality. Thus, it is important to understand and balance the trade‐off between speed and image quality. The purpose of this review is to describe how ultrafast imaging works, the potential pitfalls, current solutions to overcome the challenges, and the key applications. J. Magn. Reson. Imaging 2010;32:252–266. © 2010 Wiley‐Liss, Inc.