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Hepatic vascular flow measurements by phase contrast MRI and doppler echography: A comparative and reproducibility study
Author(s) -
Yzet Thierry,
Bouzerar Roger,
Allart JeanDominique,
Demuynck Fabien,
Legallais Cécile,
Robert Brice,
Deramond Hervé,
Meyer MarcEtienne,
Balédent Olivier
Publication year - 2010
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.22079
Subject(s) - reproducibility , doppler effect , medicine , phase contrast microscopy , magnetic resonance imaging , blood flow , radiology , ultrasound , nuclear medicine , doppler ultrasound , biomedical engineering , physics , chemistry , chromatography , astronomy , optics
Purpose: To directly compare and study the variability of parameters related to hepatic blood flow measurements using 3 T phase‐contrast magnetic resonance imaging (PC‐MRI) and Doppler ultrasound (US). Materials and Methods: Nine healthy subjects were studied. Blood velocities and flow rate measurements were performed in the portal vein and the proper hepatic artery. MR studies were performed using a 3 T imager. Gradient‐echo fast phase contrast sequences were used with both cardiac and respiratory gating. MR and Doppler flow parameters were extracted and compared. Two methods of calculation were used for Doppler flow rate analysis. Results: Compared to Doppler US, PC‐MRI largely underestimated hepatic flow data with lower variability and higher reproducibility. This reproducibility was more pronounced in the portal vein than in the proper hepatic artery associated with poorer velocity correlations. Total hepatic flow values were 1239 ± 223 mL/min and 1595 ± 521 mL/min for PC‐MRI and Doppler US, respectively. Conclusion: Free‐breathing PC‐MRI can provide reliable noninvasive measurement of hepatic flow parameters compared to Doppler US. The MR technique could help to improve Doppler flow calculations, thereby allowing standardization of protocols, particularly for applications in disease. J. Magn. Reson. Imaging 2010;31:579–588. © 2010 Wiley‐Liss, Inc.