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Three‐dimensional (3D) visualization of endolymphatic hydrops after intratympanic injection of Gd‐DTPA: Optimization of a 3D‐real inversion‐recovery turbo spin‐echo (TSE) sequence and application of a 32‐channel head coil at 3T
Author(s) -
Naganawa Shinji,
Ishihara Shunichi,
Iwano Shingo,
Sone Michihiko,
Nakashima Tsutomu
Publication year - 2010
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.22012
Subject(s) - endolymphatic hydrops , imaging phantom , meniere's disease , visualization , perilymph , nuclear medicine , medicine , biomedical engineering , materials science , computer science , nuclear magnetic resonance , inner ear , radiology , physics , artificial intelligence , surgery , vertigo
Abstract Purpose: To enable volume visualization of endolymphatic hydrops of Ménière's disease via a volume rendering (VR) technique, a three‐dimensional (3D) inversion‐recovery (IR) sequence with real reconstruction (3D‐real IR) sequence after intratympanic injection of Gd‐DTPA was optimized for higher spatial resolution using a 32‐channel head coil at 3T. Materials and Methods: Pulse sequence parameters were optimized using a diluted Gd‐DTPA phantom. Then, 11 patients who had been clinically diagnosed with Ménière's disease and a patient with sudden hearing loss were scanned. Images were processed using commercially available 3D‐VR software. 3D‐real IR data was processed to produce endolymph and perilymph fluid volume images in different colors. 3D‐CISS data was processed to generate total fluid volume images. Results: While maintaining a comparable signal‐to‐noise ratio (SNR) and scan time, the voxel volume could be reduced from 0.4 × 0.4 × 2 mm 3 with a 12‐channel coil to 0.4 × 0.4 × 0.8 mm 3 with a 32‐channel coil. A newly‐optimized protocol allowed the smooth, three‐dimensional visualization of endolymphatic hydrops in all patients with Ménière's disease. Conclusion: Volumetrically separate visualization of endo‐/perilymphatic space is now feasible in patients with Ménière's disease using an optimized 3D‐real IR sequence, a 32‐channel head coil, at 3T, after intratympanic administration of Gd‐DTPA. This will aid the understanding of the pathophysiology of Ménière's disease. J. Magn. Reson. Imaging 2010;31:210–214. © 2009 Wiley‐Liss, Inc.