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Susceptibility weighted imaging with multiple echoes
Author(s) -
Denk Christian,
Rauscher Alexander
Publication year - 2010
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21995
Subject(s) - physics , echo (communications protocol) , filter (signal processing) , phase (matter) , signal to noise ratio (imaging) , nuclear magnetic resonance , visibility , spin echo , equidistant , computation , computer science , magnetic resonance imaging , optics , mathematics , computer vision , algorithm , radiology , medicine , geometry , computer network , quantum mechanics
Purpose: To extend susceptibility weighted imaging (SWI) to multiple echoes with an adapted homodyne filtering of phase images for the computation of venograms with improved signal to noise ratio (SNR) and contrast to noise ratio (CNR) and to produce high resolution maps of R 2 * relaxation. Materials and Methods: Three‐dimensional multi echo gradient echo data were acquired with five equidistant echoes ranging from 13 to 41 ms. The phase images of each echo were filtered with filter parameters adjusted to the echo time, converted into a phase mask, and combined with the corresponding magnitude images to obtain susceptibility weighted images. The individual images were then averaged. Conventional single echo data were acquired for comparison. Maps of R 2 * relaxation rates were computed from the magnitude data. Field maps derived from the phase data were used to correct R 2 * for the influences from background inhomogeneities of the static magnetic field. Results: Compared with the single echo images, the combined images had an increase in SNR by 46% and an improvement in CNR by 34 to 80%, improved visibility of small venous vessels and reduced blurring along the readout direction. The R 2 * values of different tissue types are in good agreement with values from the literature. Conclusion: Acquisition of SWI with multiple echoes leads to an increase in SNR and CNR and it allows the computation of high resolution maps of R 2 * relaxation. J. Magn. Reson. Imaging 2010;31:185–191. © 2009 Wiley‐Liss, Inc.