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Multicontrast late gadolinium enhancement imaging enables viability and wall motion assessment in a single acquisition with reduced scan times
Author(s) -
Connelly Kim A.,
Detsky Jay S.,
Graham John J.,
Paul Gideon,
Vijayaragavan Ram,
Dick Alexander J.,
Wright Graham A.
Publication year - 2009
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21907
Subject(s) - steady state free precession imaging , nuclear medicine , medicine , magnetic resonance imaging , ejection fraction , radiology , nuclear magnetic resonance , cardiology , physics , heart failure
Purpose To determine the accuracy of multicontrast late enhancement imaging (MCLE) in the assessment of myocardial viability and wall motion compared to the conventional wall motion and viability cardiac magnetic resonance imaging (MRI) pulse sequences. Materials and Methods Forty‐one patients with suspected myocardial infarction were studied. Patients underwent assessment of cardiac function with cine steady‐state free‐precession (SSFP), followed by late gadolinium enhancement (LGE) imaging using inversion recovery gradient echo scanning (IR‐GRE) sequence and MCLE. MCLE was compared to cine SSFP in the assessment of wall motion, ejection fraction (EF), left ventricular (LV) mass, LV end‐diastolic volume (EDV), and to IR‐GRE for measuring infarct size. Results MCLE, IR‐GRE, and SSFP imaging demonstrated excellent agreement in the assessment of EF, LV infarct size, and LV mass ( r > 0.95, P < 0.001 for all measures), as well as in the assessment of wall motion (κ statistic 0.75). Conclusion MCLE provided coregistered images for the assessment of viability and wall motion without loss of accuracy in the assessment of quantitative cardiac parameters. MCLE provides accurate quantitative cardiac assessment with reduced scan times compared to the conventional sequences and thus may be used as an alternative to conventional cine SSFP and IR‐GRE imaging. J. Magn. Reson. Imaging 2009;30:771–777. © 2009 Wiley‐Liss, Inc.