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Protective effects of vitamins C and E on spermatogenesis of 1.5 Tesla magnetic field exposed rats
Author(s) -
Monfared Ali Shabestani,
Jorsaraei Seyed Gholam Ali,
Abdi Rooholah
Publication year - 2009
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21853
Subject(s) - spermatogenesis , magnetic resonance imaging , vitamin e , sperm , germ , vitamin , andrology , vitamin c , germ cell , medicine , chemistry , nuclear medicine , nuclear magnetic resonance , biology , endocrinology , antioxidant , radiology , physics , biochemistry , microbiology and biotechnology , gene
Purpose To investigate protective effects of vitamins E and C against 1.5 Tesla static magnetic fields in magnetic resonance imaging (MRI) on spermatogenesis parameters was the main goal of the present study. Materials and Methods Ninety‐two mature male rats were exposed to 1.5 T MRI static magnetic fields for 30 min with or without vitamins C and E alone or in combination. Animals were sacrificed and the testicular tissues were anatomically sectioned, stained, and the number of germ cells and the diameters of sperm ducts were measured and compared with sham and controls. Results Results showed that compared to sham, static magnetic fields may reduce the germ cell count ( P = 0.000) and sperm ducts diameters ( P = 0.020), and vitamins C and E could modify the reduction in germ cell count ( P = 0.019) but they did not show any protective effect on sperm duct diameter reduction (0.647). Conclusion The protective effects of vitamins C and E are different, and depend on the type of effects. It seems that the modifying effects of vitamins are to be additive, but vitamin E plays a more important role than vitamin C against the static magnetic field on spermatogenesis parameters in clinical MRI. J. Magn. Reson. Imaging 2009. © 2009 Wiley‐Liss, Inc.