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Lower extremities magnetic resonance angiography with blood pressure cuff compression: Quantitative dynamic analysis
Author(s) -
KoenigkamSantos Marcel,
Sharma Puneet,
Kalb Bobby,
Carew John,
Oshinski John N.,
Martin Diego
Publication year - 2009
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21777
Subject(s) - medicine , magnetic resonance angiography , magnetic resonance imaging , vascular closure device , radiology , cuff , soft tissue , nuclear medicine , femoral artery , surgery
Purpose To quantitatively evaluate changes induced by the application of a femoral blood‐pressure cuff (BPC) on run‐off magnetic resonance angiography (MRA), which is a method generally previously proposed to reduce venous contamination in the leg. Materials and Methods This study was Health Insurance Portability and Accountability Act (HIPAA)‐ and Institutional Review Board (IRB)‐compliant. We used time‐resolved gradient‐echo gadolinium (Gd)‐enhanced MRA to measure BPC effects on arterial, venous, and soft‐tissue enhancement. Seven healthy volunteers (six men) were studied with the BPC applied at the mid‐femoral level unilaterally using a 1.5T MR system after intravenous injection of Gd‐BOPTA. Different statistical tools were used such as the Wilcoxon signed rank test and a cubic smoothing spline fit. Results We found that BPC application induces delayed venous filling (as previously described), but also induces significant decreases in arterial inflow, arterial enhancement, vascular‐soft tissue contrast, and delayed peak enhancement (which have not been previously measured). Conclusion The potential benefits from using a BPC for run‐off MRA must be balanced against the potential pitfalls, elucidated by our findings. J. Magn. Reson. Imaging 2009;29:1450–1456. © 2009 Wiley‐Liss, Inc.