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High‐resolution fMRI with higher‐order generalized series imaging and parallel imaging techniques (HGS‐parallel)
Author(s) -
Yun SungDae,
Oh Sung Suk,
Han Yeji,
Park HyunWook
Publication year - 2009
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21722
Subject(s) - computer science , echo planar imaging , distortion (music) , artificial intelligence , aliasing , image resolution , temporal resolution , real time mri , computer vision , algorithm , pattern recognition (psychology) , magnetic resonance imaging , physics , optics , undersampling , bandwidth (computing) , medicine , amplifier , computer network , radiology
Purpose To develop a novel approach for high‐resolution functional MRI (fMRI) using the conventional gradient‐echo sequence. Materials and Methods Echo‐planar imaging (EPI) techniques have generally been used for fMRI studies due to their fast imaging time. However, it is difficult for studying brain function at the submillimeter level using this sequence. In addition, EPI techniques have some drawbacks, such as Nyquist ghosts and geometric distortions in the reconstructed images, and subsequently require additional postprocessing to reduce these artifacts. One way of solving these problems is to acquire fMRI data by means of a conventional gradient‐echo imaging sequence instead of EPI. To provide a fast imaging time, the proposed method combines higher‐order generalized series (HGS) imaging with a parallel imaging technique which is called the HGS‐parallel technique. Results The proposed HGS‐parallel technique achieves a 12.8‐fold acceleration in imaging time without the cost of spatial resolution. The proposed method was verified through the application of fMRI studies on normal subjects. Conclusion This study suggests that the proposed method can be used for high‐resolution fMRI studies without the geometric distortion and the Nyquist ghost artifacts compared to EPI. J. Magn. Reson. Imaging 2009;29:924–936. © 2009 Wiley‐Liss, Inc.