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Characterization of chondroblastic osteosarcoma: Gadolinium‐enhanced versus diffusion‐weighted MR imaging
Author(s) -
Yakushiji Toshitake,
Oka Kiyoshi,
Sato Hiro,
Yorimitsu Shigeta,
Fujimoto Toru,
Yamashita Yasuyuki,
Mizuta Hiroshi
Publication year - 2009
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21703
Subject(s) - gadolinium , osteosarcoma , medicine , diffusion mri , magnetic resonance imaging , radiology , nuclear medicine , pathology , materials science , metallurgy
Abstract Purpose To detect differences in magnetic resonance imaging (MRI) between chondroblastic osteosarcoma and the other types of osteosarcomas or chondrosarcomas using gadolinium‐enhanced versus diffusion‐weighted sequences. Materials and Methods Contrast‐enhanced MRI and diffusion‐weighted imaging (DWI) were performed in five chondroblastic osteosarcoma (CO) cases, 17 other types of osteosarcomas (OS), and 18 chondrosarcomas (CS). DWI was obtained with a single‐shot echo‐planar imaging (EPI) sequence using a 1.5T MR imager. The apparent diffusion coefficients (ADCs) of the minimum and maximum values were also obtained. The contrast‐enhancement pattern was evaluated and minimum‐maximum ADC value of CO was compared with other types of OS and CS. Results Both CO and CS showed a similar enhancement pattern; both showed septonodular and peripheral rim enhancement. The minimum ADC value of CO (1.24 ± 0.10 × 10 −3 mm 2 /sec) was significantly higher than that of other types of OS (0.84 ± 0.15 × 10 −3 mm 2 /sec) and was significantly lower than that of CS (1.64 ± 0.20 × 10 −3 mm 2 /sec). In addition, the maximum ADC value of CO (2.28 ± 0.20 × 10 −3 mm 2 /sec) was significantly higher than that of other types of OS (1.33 ± 0.26 × 10 −3 mm 2 /sec). Conclusion DWI appears to be more useful for differentiating between chondroblastic osteosarcoma and chondrosarcoma or other types of osteosarcoma than Gd‐enhanced MRI. J. Magn. Reson. Imaging 2009;29:895–900. © 2009 Wiley‐Liss, Inc.