Premium
Diffusion tensor imaging of kidneys with respiratory triggering: Optimization of parameters to demonstrate anisotropic structures on fraction anisotropy maps
Author(s) -
Kataoka Masako,
Kido Aki,
Yamamoto Akira,
Nakamoto Yuji,
Koyama Takashi,
Isoda Hiroyoshi,
Maetani Yoji,
Umeoka Shigeaki,
Tamai Ken,
Saga Tsuneo,
Morisawa Nobuko,
Mori Susumu,
Togashi Kaori
Publication year - 2009
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21669
Subject(s) - fractional anisotropy , diffusion mri , medulla , cortex (anatomy) , respiratory system , nuclear medicine , anisotropy , nuclear magnetic resonance , renal cortex , anatomy , medicine , kidney , chemistry , magnetic resonance imaging , physics , neuroscience , radiology , biology , optics
Purpose To demonstrate the feasibility of diffusion tensor imaging (DTI) of kidneys with respiratory triggering, and determine the optimal imaging parameters for fraction anisotropy (FA) maps. Materials and Methods DTI of kidneys from 16 healthy volunteers was performed using a 1.5T scanner. Five different sequences with different parameters including respiration‐triggered acquisition or multiple breath‐holding, slice thicknesses of 3 or 5 mm, and different numbers of signal averaging and b values were compared. FA and apparent diffusion coefficients (ADCs) of the cortex and medulla were measured. Measurement error within the same and repeated examination was examined using within‐individual standard deviation (Sw). Results FAs of the renal cortex were lower than the medulla (mean value of a sequence ranging 0.148–0.224, 0.433–0.476) and the ADCs of the cortex were higher than the medulla (2.26–2.69 × 10 −3 mm 2 /s, 1.77–2.19 × 10 −3 mm 2 /s) in all sequences ( P < 0.001). The renal cortex–medulla difference was the largest, with respiratory trigger‐ ing including a 3‐mm slice thickness, three signal averages,and a b‐value = 0, 200, or 400 s/mm 2 ( P < 0.001). Sw tended to be smaller in the sequence with a b‐value of 400 s/mm 2 . Conclusion DTI of kidneys with respiratory triggering is feasible with excellent cortex–medulla differentiation. J. Magn. Reson. Imaging 2009;29:736–744. © 2009 Wiley‐Liss, Inc.