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Calibrated magnetic resonance hydrometry to quantify pancreatic juice: A preliminary study
Author(s) -
Jin Enhao,
Ichikawa Tomoaki,
Erturk Sukru Mehmet,
Motosugi Utaroh,
Hirano Masaya,
Araki Tsutomu
Publication year - 2009
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21614
Subject(s) - in vivo , magnetic resonance imaging , correlation coefficient , volume (thermodynamics) , nuclear magnetic resonance , saline , nuclear medicine , chemistry , proton magnetic resonance , materials science , biomedical engineering , medicine , physics , mathematics , radiology , biology , statistics , microbiology and biotechnology , quantum mechanics
Purpose To investigate the effectiveness of the calibrated MR hydrometry (CMRH) method for accurately measuring pancreatic secretion. Materials and Methods All studies were performed on a 1.5‐T MR system using a fat‐suppressed, single‐shot half‐Fourier fast spin‐echo sequence with a standard body coil. A certain volume (20 mL) of saline solution was employed as an extrabody calibrator. The validity of the CMRH method was tested both in vitro and in vivo, and actual and calculated volumes were compared. Results The in vitro study yielded a high correlation ( r = 0.99; P < 0.0001) between the actual volume of saline solution in the imaging field and the calculated volume. In the in vivo study, for all volunteers, there was a very strong and significant positive correlation between the measured signal intensities or calculated volumes and actual volumes (correlation coefficient range: 0.94–0.99; P < 0.0001). Conclusion This preliminary study shows that CMRH is an effective tool to measure the amount of pancreatic fluid secretion. J. Magn. Reson. Imaging 2009;29:217–220. © 2008 Wiley‐Liss, Inc.