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Free‐breathing high‐spatial‐resolution delayed contrast‐enhanced three‐dimensional viability MR imaging of the myocardium at 3.0T: A feasibility study
Author(s) -
Amano Yasuo,
Matsumura Yoshio,
Kumita Shinichiro
Publication year - 2008
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21595
Subject(s) - contrast (vision) , breathing , medicine , biomedical engineering , magnetic resonance imaging , image resolution , nuclear medicine , radiology , computer science , anatomy , artificial intelligence
Abstract Purpose To assess the feasibility of free‐breathing high‐spatial‐resolution delayed contrast‐enhanced three‐dimensional (3D) viability magnetic resonance imaging (MRI) at 3.0T for the detection of myocardial damages. Materials and Methods Twenty‐five patients with myocardial diseases, including myocardial infarction and cardiomyopathies, were enrolled after informed consent was given. Free‐breathing 3D viability MRI with high spatial resolution (1.5 × 1.25 × 2.5 mm) at 3.0T, for which cardiac and navigator gating techniques were employed, was compared with breath‐hold two‐dimensional (2D) viability imaging (1.77 × 1.18 × 10 mm) for assessment of contrast‐to‐noise ratio (CNR) and myocardial damage. Results Free‐breathing 3D viability imaging was achieved successfully in 21 of the 25 patients. This imaging technique depicted 84.6% of hyperenhancing myocardium with a higher CNR between hyperenhancing myocardium and blood and with excellent agreement for the transmural extension of myocardial damage (k = 0.91). In particular, the 3D viability images delineated the myocardial infarction and linear hyperenhancing myocardium, comparable to the 2D viability images. Conclusion Free‐breathing high‐spatial‐resolution delayed contrast‐enhanced 3D viability MRI using 3.0T was feasible for the evaluation of hyperenhancing myocardium, as seen with myocardial infarction and cardiomyopathies. J. Magn. Reson. Imaging 2008;28:1361–1367. © 2008 Wiley‐Liss, Inc.