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Single breath‐hold multiarterial dynamic MRI of the liver at 3T using a 3D fat‐suppressed keyhole technique
Author(s) -
Hong HyeSuk,
Kim Hua Sun,
Kim MyeongJin,
De Becker Jan,
Mitchell Donald G.,
Kanematsu Masayuki
Publication year - 2008
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21442
Subject(s) - keyhole , medicine , homogeneous , lesion , radiology , peripheral , nodule (geology) , focal nodular hyperplasia , nuclear medicine , high resolution , hepatocellular carcinoma , pathology , materials science , physics , paleontology , remote sensing , welding , biology , metallurgy , thermodynamics , geology
Purpose To evaluate the feasibility of single breath‐hold, multiarterial MRI of the liver using the THRIVE‐CENTRA‐keyhole technique. Materials and Methods Twenty‐eight patients with 63 focal hepatic lesions underwent liver MR examinations that included the three‐dimensional THRIVE‐CENTRA‐keyhole sequence. Three or six phases were obtained for arterial phase scanning during a single breath‐hold. Central k‐space data were collected for each phase but the remaining peripheral k‐space data were collected only once. The enhancement pattern of each hepatic lesion was analyzed according to the specific diagnosis. Results Hepatocellular carcinomas ( n = 24) enhancement patterns included: rim enhancing ( n = 9), homogeneous ( n = 7), nodule‐in‐nodule ( n = 5), or heterogeneous ( n = 3). A late peritumoral rim was observed in four (17%) of the hepatocellular carcinomas. Most metastases (17 of 18; 94%) demonstrated peripheral rim enhancement. The progressive centripetal enhancement of hemangiomas ( n = 6) was clearly depicted. Focal nodular hyperplasia ( n = 4) showed early homogeneous enhancement and one lesion demonstrated a central scar. Conclusion The THRIVE‐CENTRA‐keyhole technique can be used to acquire single breath‐hold, multiarterial images depicting improved enhancement characteristics of focal hepatic lesions. This technique will allow accurate timing of arterial scanning with 3D acquisition and high temporal resolution. J. Magn. Reson. Imaging 2008;28:396–402. © 2008 Wiley‐Liss, Inc.