z-logo
Premium
Feasibility and reproducibility of relaxometry, morphometric, and geometrical measurements of the hip joint with magnetic resonance imaging at 3T
Author(s) -
CarballidoGamio Julio,
Link Thomas M.,
Li Xiaojuan,
Han Eric T.,
Krug Roland,
Ries Michael D.,
Majumdar Sharmila
Publication year - 2008
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21411
Subject(s) - reproducibility , magnetic resonance imaging , femoral head , cartilage , osteoarthritis , medicine , relaxometry , nuclear medicine , t2 relaxation , biomedical engineering , radiology , anatomy , pathology , chemistry , spin echo , alternative medicine , chromatography
Purpose To test the feasibility of in vivo magnetic resonance T 1ρ relaxation time measurements of hip cartilage, and quantify the reproducibility of hip cartilage thickness, volume, T 2 , T 1ρ , and size of femoral head measurements. Materials and Methods The hip joint of five human healthy volunteers, one subject with mild hip osteoarthritis (OA) and one subject with advanced hip OA, was imaged with magnetic resonance imaging (MRI) at 3T. Hip cartilage thickness, volume, T 1ρ , and T 2 were quantified, as well as the size of the femoral head. All imaging and analysis procedures were performed twice for the healthy volunteers to assess reproducibility. Results In vivo MR T 1ρ measurements of hip cartilage at 3T were feasible as demonstrated by high quality images and relaxation time maps. High levels of reproducibility were obtained for measurements of hip cartilage thickness (CV SD = 2.19%), volume (CV SD = 3.5%), T 2 (CV SD = 5.89%), T 1ρ (CV SD = 2.03%), and size of femoral head (CV SD = 0.49%). Mean T 2 and T 1ρ relaxation time values for human healthy subjects were 28.38 (±2.66) msec and 38.72 (±3.84) msec, respectively. Mean T 2 and T 1ρ relaxation time values for subjects with OA were 34.78 (±8.36) msec and 44.07 (±0.99) msec, respectively. T 2 and T 1ρ values increased from the deep to the superficial layers. Conclusion Qualitative and quantitative results indicate that the MRI techniques presented in this study may be applied clinically to patients with OA of the hip to investigate these parameters at different stages of disease. J. Magn. Reson. Imaging 2008;28:227–235. © 2008 Wiley‐Liss, Inc.

This content is not available in your region!

Continue researching here.

Having issues? You can contact us here