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Reproducibility of MRI measurements of right ventricular size and function in patients with normal and dilated ventricles
Author(s) -
Mooij Christiaan F.,
de Wit Cornelis J.,
Graham Dionne A.,
Powell Andrew J.,
Geva Tal
Publication year - 2008
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21407
Subject(s) - reproducibility , intraclass correlation , medicine , tetralogy of fallot , cardiology , ejection fraction , stroke volume , magnetic resonance imaging , nuclear medicine , radiology , heart failure , heart disease , chemistry , chromatography
Purpose To determine the inter‐ and intraobserver reproducibility of cardiac magnetic resonance (CMR)‐derived measurements of right ventricular (RV) mass, volume, and function in patients with normal and dilated ventricles. Materials and Methods CMR studies of 60 patients in three groups were studied: a normal RV group ( N = 20) and two groups with RV dilation—atrial septal defect (ASD) ( N = 20) and repaired tetralogy of Fallot (TOF) ( N = 20). Two independent observers analyzed each study on two separate occasions. Inter‐ and intraobserver reproducibility of biventricular mass, volume, ejection fraction (EF), and stroke volume (SV) measurements were calculated. Results High intraclass correlation coefficients (ICC) were found for interobserver (ICC = 0.94–0.99) and intraobserver (ICC = 0.96–0.99) comparisons of RV and left ventricular (LV) mass, volume, and SV measurements. RV and LV EF measurements were less reproducible (ICC = 0.79–0.87). RV mass measurements were significantly less correlated than the respective LV measurements. Small but statistically significant differences in correlation were noted in RV measurements across groups. Conclusion Except for RV mass, inter‐ and intraobserver reproducibility of RV size and function measurements is high and generally comparable to that in the LV in patients with both normal and dilated RV. J. Magn. Reson. Imaging 2008;28:67–73. © 2008 Wiley‐Liss, Inc.