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Reducing morphological variability of the cervical carotid artery in serial magnetic resonance imaging using a head and neck immobilization device
Author(s) -
Chapman Brian E.,
Minalga Emilee S.,
Brown Christopher,
Roberts John A.,
Hadley J. Rock
Publication year - 2008
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21404
Subject(s) - medicine , carotid arteries , magnetic resonance imaging , lumen (anatomy) , orientation (vector space) , radiology , head and neck , common carotid artery , biomedical engineering , nuclear medicine , cardiology , surgery , geometry , mathematics
Purpose To evaluate how well a head and neck immobilization device performed in reducing lumen morphology variability in repeated MR imaging of the carotid artery. Materials and Methods Quantitative measures of lumen and plaque characteristics may be important for longitudinal management of carotid atherosclerotic disease. However, quantitative measurements of the carotid artery are limited by their dependence on patient positioning, which can be quite variable. We created a head and neck immobilization device to reduce the variability of patient positioning during MR imaging of the carotid artery. In this article we describe the design and use of the immobilization device and assess how well its use reduced variability in vascular orientation and measurements of the carotid lumen cross‐sectional area. Evaluation was based on 15 subjects who were repeatedly imaged without the immobilization device and 14 subjects who were repeatedly imaged with the device. Results Use of the immobilization device decreased the orientation variability from 9.1° to 5.3° ( P = 0.0006) and the variability (defined as the standard deviation divided by the mean) of the cross‐sectional area decreased from 0.24 to 0.18 ( P = 0.04). Conclusion Using the immobilization device effectively reduces variability in repeated imaging of the carotid arteries. J. Magn. Reson. Imaging 2008;28:258–262. © 2008 Wiley‐Liss, Inc.