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Tumor‐liver contrast and subjective tumor conspicuity of respiratory‐triggered T2‐weighted fast spin‐echo sequence compared with T2*‐weighted gradient recalled‐echo sequence for ferucarbotran‐enhanced magnetic resonance imaging of hepatic malignant tumors
Author(s) -
Ishiyama Koichi,
Hashimoto Manabu,
Izumi Junichi,
Watarai Jiro,
Shibata Satoshi,
Sato Tsutomu,
Yamamoto Yuzo
Publication year - 2008
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21399
Subject(s) - medicine , t2 weighted , magnetic resonance imaging , fast spin echo , gradient echo , nuclear medicine , lesion , radiology , wilcoxon signed rank test , pathology , mann–whitney u test
Purpose To compare respiratory‐triggered T2‐weighted fast spin‐echo (RTT2W‐FSE) and gradient T2*‐weighted recalled‐echo (T2*W‐GRE) images for visualization of malignant hepatic tumors using ferucarbotran‐enhanced magnetic resonance (MR) imaging. Materials and Methods Ferucarbotran‐enhanced RTT2W‐FSE and breath‐hold long‐TE 2D‐fast spoiled gradient recalled acquisition in the steady state (FSPGR) images as T2*W‐GRE were used to evaluate 128 malignant hepatic tumors (77 metastases, 37 hepatocellular carcinomas, 14 other) in 62 patients. Tumor‐to‐liver contrast (TLC) was quantitatively compared using the paired Student's t ‐test, and the score of lesion conspicuity was qualitatively compared using Wilcoxon's signed rank test. Results The mean TLC of RTT2W‐FSE was significantly higher than that of FSPGR (1.10 ± 0.82 vs. 2.54 ± 1.42) in all malignant tumors. The score of lesion conspicuity of RTT2W‐FSE was significantly higher than that of FSPGR (4.84 ± 0.52 vs. 4.52 ± 0.99) in all malignant tumors. Conclusion For ferucarbotran‐enhanced MR imaging, compared to FSPGR images, RTT2W‐FSE images provide greater TLC and subjective conspicuity for malignant tumors. J. Magn. Reson. Imaging 2008;27:1322–1326. © 2008 Wiley‐Liss, Inc.