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Delayed enhancement in hypertrophic cardiomyopathy: Comparison with myocardial tagging MRI
Author(s) -
Kim Young Jin,
Choi Byoung Wook,
Hur Jin,
Lee HyeJeong,
Seo Jae Seung,
Kim Tae Hoon,
Choe Kyu Ok,
Ha JongWon
Publication year - 2008
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21366
Subject(s) - hypertrophic cardiomyopathy , medicine , myocardial fibrosis , muscle hypertrophy , cardiomyopathy , nuclear medicine , magnetic resonance imaging , cardiology , radiology , fibrosis , heart failure
Purpose To evaluate the relationship between delayed enhancement (DE) and regional left ventricular function in hypertrophic cardiomyopathy (HCM) using gadolinium enhancement MRI and myocardial tagging MRI. Materials and Methods Cine imaging, delayed enhancement imaging, and tagging MRI were performed in 25 patients with HCM. The location, pattern, and extent of DE were evaluated. Circumferential shortening (Ecc) was obtained by analyzing MR tagging images with HARP software. Results DE occurred in 21 (84%) patients with a high frequency of localization in the septum and the right ventricular attachment sites. Circumferential shortening was significantly decreased in the enhanced segments compared with nonenhanced segments ( P < 0.0001). The myocardial wall was thicker in the enhanced segments than in the nonenhanced segments ( P < 0.0001). However, circumferential shortening was significantly decreased in the enhanced segments of the same thickness ( P < 0.0001). Circumferential shortening was more substantially impaired in the segments with focal nodular enhancement than those in the segments with ill‐defined patchy enhancement ( P = 0.0002). Conclusion In HCM, DE is commonly found and circumferential shortening is significantly impaired in the regions with DE, regardless of the degree of myocardial hypertrophy. Focal nodular enhancement is particularly related with regional dysfunction in patients with HCM. J. Magn. Reson. Imaging 2008;27:1054–1060. © 2008 Wiley‐Liss, Inc.