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3D myocardial tissue tracking with slice followed cine DENSE MRI
Author(s) -
Spottiswoode Bruce S.,
Zhong Xiaodong,
Lorenz Christine H.,
Mayosi Bongani M.,
Meintjes Ernesta M.,
Epstein Frederick H.
Publication year - 2008
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21317
Subject(s) - tracking (education) , imaging phantom , displacement (psychology) , rotation (mathematics) , match moving , cardiac cycle , biomedical engineering , plane (geometry) , physics , nuclear medicine , materials science , motion (physics) , computer science , artificial intelligence , medicine , mathematics , geometry , cardiology , pedagogy , psychotherapist , psychology
Purpose To track three‐dimensional (3D) myocardial tissue motion using slice followed cine displacement encoded imaging with stimulated echoes (DENSE). Materials and Methods Slice following (SF) has previously been developed for 2D myocardial tagging to compensate for the effect of through‐plane motion on 2D tissue tracking. By incorporating SF into a cine DENSE sequence, and applying displacement encoding in three orthogonal directions, we demonstrate the ability to track discrete elements of a slice of myocardium in 3D as the heart moves through the cardiac cycle. The SF cine DENSE tracking algorithm was validated on a moving phantom, and the effects of through‐plane motion on 2D cardiac strain were investigated in six healthy subjects. Results A through‐plane tracking accuracy of 0.46 ± 0.32 mm was measured for a typical range of myocardial motion using a rotating phantom. In vivo 3D measurements of cardiac motion were consistent with prior myocardial tagging results. Through‐plane rotation in a mid‐ventricularshort‐axis view was shown to decrease the magnitude of the 2D end‐systolic circumferential strain by 3.91 ± 0.43% and increase the corresponding radial strain by 6.01 ± 1.07%. Conclusion Slice followed cine DENSE provides an accurate method for 3D tissue tracking. J. Magn. Reson. Imaging 2008;27:1019–1027. © 2008 Wiley‐Liss, Inc.