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Stem cell therapy: MRI guidance and monitoring
Author(s) -
Kraitchman Dara L.,
Gilson Wesley D.,
Lorenz Christine H.
Publication year - 2008
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21263
Subject(s) - magnetic resonance imaging , stem cell therapy , stem cell , computer science , medicine , translation (biology) , medical physics , pathology , radiology , mesenchymal stem cell , biology , genetics , biochemistry , messenger rna , gene
With the recent advances in magnetic resonance (MR) labeling of cellular therapeutics, it is natural that interventional MRI techniques for targeting would be developed. This review provides an overview of the current methods of stem cell labeling and the challenges that are created with respect to interventional MRI administration. In particular, stem cell therapies will require specialized, MR‐compatible devices as well as integration of graphical user interfaces with pulse sequences designed for interactive, real‐time delivery in many organs. Specific applications that are being developed will be reviewed as well as strategies for future translation to the clinical realm. J. Magn. Reson. Imaging 2008;27:299–310. © 2008 Wiley‐Liss, Inc.