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Laser Doppler velocimetry (LDV) and 3D phase‐contrast magnetic resonance angiography (PC‐MRA) velocity measurements: Validation in an anatomically accurate cerebral artery aneurysm model with steady flow
Author(s) -
Hollnagel Dorothea I.,
Summers Paul E.,
Kollias Spyros S.,
Poulikakos Dimos
Publication year - 2007
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21179
Subject(s) - phase contrast microscopy , magnetic resonance angiography , velocimetry , physics , doppler effect , flow velocity , laser doppler velocimetry , aneurysm , magnetic resonance imaging , nuclear magnetic resonance , scanner , angiography , flow (mathematics) , radiology , medicine , blood flow , optics , mechanics , astronomy
Purpose To verify the accuracy of velocity mapping with three‐dimensional (3D) phase‐contrast magnetic resonance angiography (PC‐MRA) for steady flow in a realistic model of a cerebral artery aneurysm at a 3T scanner. Materials and Methods Steady flow through an original geometry model of a cerebral aneurysm was mapped at characteristic positions by state‐of‐the‐art laser Doppler velocimetry (LDV) as well as 3D PC‐MRA at 3T. The spatial distributions and local values of two velocity components obtained with these two measurement methods were compared. Results The 3D PC‐MRA velocity field distribution and mean velocity values exhibited only minor differences to compare to the LDV measurements in straight artery regions for both main and secondary velocities. The differences increased in regions with disturbed flow and in cases where the measurement plane was not perpendicular to the main flow direction. Conclusion 3D PC‐MRA can provide reliable measurements of velocity components of steady flow in small arteries. The accuracy of such measurements depends on the artery size and the measurement plane positioning. J. Magn. Reson. Imaging 2007. © 2007 Wiley‐Liss, Inc.