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MR‐guided radiofrequency ablation in a 0.2‐T open MR system: Technical success and technique effectiveness in 100 liver tumors
Author(s) -
Clasen Stephan,
Boss Andreas,
Schmidt Diethard,
Schraml Christina,
Fritz Jan,
Schick Fritz,
Claussen Claus D.,
Pereira Philippe L.
Publication year - 2007
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21120
Subject(s) - ablation , radiofrequency ablation , medicine , magnetic resonance imaging , ablative case , coagulative necrosis , rf ablation , radiology , nuclear medicine , radiation therapy , pathology
Purpose To evaluate the feasibility and technique effectiveness of magnetic resonance (MR)‐guided radiofrequency (RF) ablation of hepatic malignancies. Materials and Methods In 64 patients, 100 primary ( N = 19) or secondary ( N = 81) liver tumors (mean diameter = 24.7 mm; range = 4–60 mm) were treated with 87 sessions of MR‐guided RF ablation. The entire ablation procedure was carried out at an 0.2‐T open MR system by using MR‐compatible internally cooled electrodes. T2‐weighted turbo spin echo sequences (TR/TE = 3500 msec/110 msec) were used to monitor thermally induced coagulation. Technique effectiveness was assessed four months after the last RF ablation by dynamic MR imaging at 1.5‐T. Results MR‐guided RF ablation procedures were technical successful in 85 of 87 (97.7%) assessed at the end of each session. Complete coagulation was intended in 99 of 100 tumors. Technique effectiveness was observed in 92 of 99 (92.9%) of these tumors. To achieve complete coagulation 82 of 92 (89.1%) tumors required a single session. T2‐weighted sequences were accurate to monitor the extent of coagulation and were supportive to guide overlapping ablation. There were two of 87 (2.3%) major and seven of 87 (8.0%) minor complications. Conclusion MR‐guided RF ablation is a safe and effective therapy in the treatment of hepatic malignancies. MR imaging offers an accurate monitoring of thermally‐induced coagulation, thus enabling complete tumor coagulation in a single session. J. Magn. Reson. Imaging 2007;26:1043–1052. © 2007 Wiley‐Liss, Inc.