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Inflammatory myofibroblastic tumors in the liver: MRI of two immunohistochemically‐verified cases
Author(s) -
Yu JeongSik,
Park Chanil,
Kim Joo Hee,
Chung JaeJoon,
Kim Ki Whang
Publication year - 2007
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.21023
Subject(s) - pathology , medicine , magnetic resonance imaging , immunohistochemistry , radiology
In immunohistochemically‐proven hepatic inflammatory myofibroblastic tumors, MRI revealed layered patterns of contrast enhancement during dynamic imaging, consisting of outer hypovascular rind and inner hypervascular stroma and mimicking the imaging features of pyogenic organized abscess with deficient central necrosis in four lesions in two patients. For the outer hypovascular rind, T2‐weighted images showed hyperintensity, suggesting immature fibrosis corresponding to the area of arterial hypovascularity and delayed contrast enhancement. The patients' favorable clinical course and imaging findings reflected the benign nature of these lesions, from an infectious origin, despite the phenotypic expression of myofibroblastic proliferation in the hypervascular stroma containing chronic inflammatory cells. J. Magn. Reson. Imaging 2007. © 2007 Wiley‐Liss, Inc.