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FAIR true‐FISP perfusion imaging of the thyroid gland
Author(s) -
Schraml Christina,
Boss Andreas,
Martirosian Petros,
Schwenzer Nina F.,
Claussen Claus D.,
Schick Fritz
Publication year - 2007
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20943
Subject(s) - thyroid , medicine , perfusion , radiology , magnetic resonance imaging , perfusion scanning , pathology , nuclear medicine
Purpose To evaluate the feasibility of quantitative perfusion MRI of the thyroid gland using an arterial spin labeling (ASL) method. Materials and Methods An ASL technique with flow‐sensitive alternating inversion‐recovery (FAIR) spin preparation and a true fast imaging in the steady state (TrueFISP) signal readout strategy was implemented on a 1.5T whole‐body unit. Anatomical and perfusion imaging of the thyroid gland was performed in eight healthy volunteers and one patient with functioning adenoma. Quantitative perfusion maps were calculated using the extended Bloch equations. Results In all subjects the perfusion images showed diagnostic image quality. The mean examination time was 24 minutes for multiplanar perfusion imaging of the entire thyroid gland. Individual perfusion values ranged between 341 ± 91 and 640 ± 90 mL/100 g/minute, with a mean perfusion of 461 ± 90 mL/100 g/minute. The functioning adenoma showed markedly reduced perfusion compared to normal thyroidal parenchyma. No perfusion was noticeable inside four detected thyroid cysts. Conclusion Quantitative ASL perfusion imaging of the thyroid gland using a FAIR‐TrueFISP sequence leads to perfusion maps that may provide important information for assessing thyroid gland pathologies and monitoring therapeutic treatment. J. Magn. Reson. Imaging 2007;26:66–71. © 2007 Wiley‐Liss, Inc.