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High temporal resolution breathheld 3D FIESTA CINE imaging: Validation of ventricular function in patients with chronic myocardial infarction
Author(s) -
Rettmann Dan W.,
Saranathan Manojkumar,
Wu Katherine C.,
Azevedo Clerio F.,
Bluemke David A.,
Foo Thomas K.F.
Publication year - 2007
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20923
Subject(s) - steady state free precession imaging , medicine , ejection fraction , nuclear medicine , magnetic resonance imaging , myocardial infarction , temporal resolution , cardiology , radiology , heart failure , physics , quantum mechanics
Purpose To develop a gated single‐breathhold, high temporal resolution three‐dimensional (3D) CINE imaging technique and to evaluate its accuracy in volumetric and functional quantification in patients with chronic myocardial infarction. Materials and Methods A 3D CINE steady‐state free precession (SSFP) pulse sequence was developed incorporating variable temporal sampling of the low and high spatial frequency k‐space data to reduce breathhold time and parallel imaging to increase temporal resolution. Reconstruction with retrospective interpolation enabled complete R‐R interval coverage. Feasibility was assessed in eight patients with chronic myocardial infarction and ventricular functional values were compared to those of a 2D CINE acquisition. Results There was no significant difference between the 3D CINE and 2D CINE for end‐diastolic volume (168 ± 73 vs. 177 ± 59 mL, respectively; P < 0.27), end‐systolic volume (81 ± 62 vs. 79 ± 53 mL; P < 0.81), and ejection fraction (EF) measurements (55 ± 14% vs. 58 ± 14%; P < 0.14). The mean difference in EF was less than 2.5%. A wall motion assessment indicated a good agreement, with a weighted kappa value of 0.62. Conclusion High temporal resolution 3D CINE SSFP imaging of the whole heart can be obtained in a single breathhold and yield ventricular function measurements similar to 2D CINE methods. J. Magn. Reson. Imaging 2007;25:1141–1146. © 2007 Wiley‐Liss, Inc.