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Molecular imaging and therapy of atherosclerosis with targeted nanoparticles
Author(s) -
Wickline Samuel A.,
Neubauer Anne M.,
Winter Patrick M.,
Caruthers Shelton D.,
Lanza Gregory M.
Publication year - 2007
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20866
Subject(s) - medicine , molecular imaging , targeted therapy , nanobiotechnology , nanotechnology , nanoparticle , cancer , biology , materials science , microbiology and biotechnology , in vivo
Advances in bionanotechnology are poised to impact the field of cardiovascular diagnosis and therapy for decades to come. This review seeks to illustrate selected examples of newly developed diagnostic and therapeutic nanosystems that have been evaluated in experimental atherosclerosis, thrombosis, and vascular biology. We review a variety of nanotechnologies that are capable of detecting early cardiovascular pathology, as well as associated imaging approaches and conjunctive strategies for site‐targeted treatment with nanoparticle delivery systems. J. Magn. Reson. Imaging 2007. © 2007 Wiley‐Liss, Inc.