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Diagnosis of breast tumors by contrast‐enhanced MR imaging: Comparison between the diagnostic performance of dynamic enhancement patterns and morphologic features
Author(s) -
Goto Mariko,
Ito Hirotoshi,
Akazawa Kentaro,
Kubota Takao,
Kizu Osamu,
Yamada Kei,
Nishimura Tsunehiko
Publication year - 2007
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20812
Subject(s) - dynamic contrast , dynamic contrast enhanced mri , contrast (vision) , contrast enhancement , medicine , radiology , magnetic resonance imaging , computer science , artificial intelligence
Purpose To compare the diagnostic performance of breast lesions by the enhancement patterns and morphologic criteria on magnetic resonance imaging (MRI). Materials and Methods Both T1‐weighted 3D gradient‐echo sequences with high temporal resolution and high‐spatial‐resolution MRI were performed on 190 patients with a total of 204 enhancing lesions (144 malignant and 60 benign). The enhancement patterns and morphologic features of each mass and nonmass lesion were analyzed, and the diagnostic performance was compared. Results The sensitivity and specificity of the morphologic criteria were statistically significantly higher than those of the enhancement patterns (sensitivity: P = 0.0012, specificity: P = 0.0003), and the A z values for the three observers were 0.900, 0.919, and 0.900. The diagnostic accuracy of the morphologic criteria for both types of lesions was superior, and the differences were statistically significant (mass: P = 0.0001, nonmass: P = 0.0389). Conclusion The analysis of the morphologic features of enhancing breast lesions alone showed higher diagnostic performance; therefore, signal intensity (SI) time‐course data may not be needed to diagnose malignant breast lesions. J. Magn. Reson. Imaging 2007. © 2006 Wiley‐Liss, Inc.