Premium
Two‐dimensional population map of cortical connections in the human internal capsule
Author(s) -
Zarei Mojtaba,
JohansenBerg Heidi,
Jenkinson Mark,
Ciccarelli Olga,
Thompson Alan J.,
Matthews Paul M.
Publication year - 2007
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20810
Subject(s) - internal capsule , diffusion mri , somatosensory system , population , tractography , neuroscience , anatomy , human brain , psychology , medicine , magnetic resonance imaging , radiology , white matter , environmental health
Abstract Purpose To exploit diffusion imaging tractography to produce a two‐dimensional (xy) probabilistic population map of the cortical connections within the human internal capsule (IC). Materials and Methods Diffusion tensor imaging (DTI) was carried out on 11 healthy volunteers. We parceled an axial section of the IC according to its connections to the prefrontal, premotor, primary motor, primary somatosensory, posterior parietal, and occipital cortices using our locally developed probabilistic algorithm. Results A consistent topographical organization was generated that was consistent with our anatomical knowledge of the IC. In addition, our study shows that in humans the anterior half of the IC is occupied by the prefrontal cortex. Conclusion This map may be of clinical use for correlating neurological deficit with hemispheric lesions, particularly those that affect sensorimotor function. J. Magn. Reson. Imaging 2007. © 2006 Wiley‐Liss, Inc.