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Diagnostic accuracy of high‐resolution MRI using a microscopy coil for patients with presumed DCIS following mammography screening
Author(s) -
Zhu Jingzhi,
Kurihara Yasuyuki,
Kanemaki Yoshihide,
Ogata Haruki,
Fukuda Mamoru,
Nakajima Yasuo,
Maeda Ichiro
Publication year - 2007
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20809
Subject(s) - medicine , mammography , radiology , malignancy , breast cancer , magnetic resonance imaging , pathological , breast mri , gold standard (test) , biopsy , diagnostic accuracy , calcification , predictive value , nuclear medicine , cancer , pathology
Purpose To prospectively evaluate the accuracy of high‐resolution (HR)‐MRI as a secondary examination in women with abnormal calcifications detected on mammography. Materials and Methods We used a 4.7‐cm microscopy coil to acquire HR‐MRI signal data. We examined 52 women with breast lesions preoperatively using HR‐MRI and vacuum‐assisted core needle biopsy. The lesions were suspicious of malignancy, classified as category 3–5 on mammography (Breast Imaging Reporting and Data System [BI‐RADS]), and without a palpable mass. All visualized suspicious lesions were correlated with histological findings. We compared the HR‐MRI and pathological findings and calculated the sensitivity, specificity, and accuracy. Results We compared the breast HR‐MRI results with the gold standard of pathological results for studies of malignancy (DCIS and invasive cancer), and found a sensitivity of 88.5%, specificity of 92.3%, and accuracy of 90.4%. The positive predictive value (PPV) was 92%, and the negative predictive value (NPV) was 88.9%. When breast MRI was compared with pathological results for studies that diagnosed DCIS only, the results revealed a sensitivity of 88.6%, specificity of 88.2%, accuracy of 88.5%, PPV of 93.9%, and NPV of 78.9%. Conclusion HR‐MRI using a microscopy coil is a useful, reliable, safe, and minimally invasive procedure that is a good choice for secondary assessment of abnormal calcification in the breast. J. Magn. Reson. Imaging 2007. © 2006 Wiley‐Liss, Inc.