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Detection of hepatic metastases using ferucarbotran‐enhanced MR imaging: Feasibility and diagnostic accuracy of three‐dimensional sensitivity‐encoding water‐excitation multishot echo‐planar sequence (3D‐SWEEP)
Author(s) -
Mori Kensaku,
Takahashi Nobuyuki,
Hiratsuka Makiko,
Shiigai Masanari,
Minami Manabu,
Oda Tatsuya,
Ohkohchi Nobuhiro,
Morishita Yukio
Publication year - 2006
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20755
Subject(s) - nuclear medicine , medicine , image quality , receiver operating characteristic , magnetic resonance imaging , echo planar imaging , radiology , computer science , image (mathematics) , artificial intelligence
Purpose To evaluate the diagnostic accuracy of a ferucarbotran‐enhanced three‐dimensional sensitivity‐encoding water‐excitation multishot echo‐planar sequence (3D‐SWEEP) for detecting hepatic metastases compared to a T2*‐weighted fast field‐echo (FFE) sequence. Materials and Methods Twenty‐five consecutive patients with hepatic metastases underwent ferucarbotran‐enhanced MRI on a 1.5‐T unit before hepatic resections. Eighty‐two foci of metastases were confirmed by histopathology or intraoperative ultrasonography (US). Signal‐intensity decay (SID), tumor‐to‐liver contrast (TLC), and image quality were compared between T2*‐weighted FFE and 3D‐SWEEP. Three independent observers reviewed three imaging sets: set 1, without 3D‐SWEEP or T2*‐weighted FFE; set 2, with T2*‐weighted FFE; and set 3, with 3D‐SWEEP. The mean values of areas under alternative free response receiver operating characteristic curves (Az) and sensitivities were compared among the three sets. Results SID and TLC were significantly greater for 3D‐SWEEP than T2*‐weighted FFE, although 3D‐SWEEP had poorer image quality. The mean Az and sensitivity were significantly greater for set 3 compared to set 1 for detecting overall lesions, and compared to sets 1 and 2 for detecting lesions of 1–2 cm in diameter. Conclusion Despite relatively prominent artifacts, ferucarbotran‐enhanced 3D‐SWEEP was more sensitive and accurate than T2*‐weighted FFE for detecting hepatic metastases. J. Magn. Reson. Imaging 2006. © 2006 Wiley‐Liss, Inc.