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Strengths and weaknesses of dark‐lumen MR colonography: Clinical relevance of polyps smaller than 5 mm in diameter at the moment of their detection
Author(s) -
Ajaj Waleed,
Ruehm Stefan G.,
Gerken Guido,
Goyen Mathias
Publication year - 2006
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20734
Subject(s) - medicine , colonoscopy , radiology , dysplasia , nuclear medicine , malignancy , lumen (anatomy) , colorectal cancer , pathology , cancer
Abstract Purpose To assess the clinical relevance of dark‐lumen MR colonography (MRC) for the detection of colorectal lesions using conventional colonoscopy (CC) and histopathologic examinations as reference standard. Materials and Methods A total of 72 patients underwent MRC and CC. MRC was performed using a contrast‐enhanced high spatial resolution T1 weighted 3D volumetric interpolated breathhold examination (VIBE)‐sequence. All removed colorectal lesions were evaluated by an experienced pathologist. Results CC confirmed 65 polyps less than 5 mm in diameter. Non of those lesions could be detected using MRC. Just two (4%) of the 49 removed lesions smaller than 5 mm showed signs of dysplasia. Additionally, CC confirmed 25 polyps between 6–15 mm in diameter (MRC 22). All those 25 lesions were removed in CC. Only four (16%) of those polyps showed signs of dysplasia and malignancy (11, 13, 13 and 15 mm). Conclusion Dark‐lumen MRC failed to detect all polyps smaller than 5 mm in diameter which are generally not clinically relevant at the moment of their detection and thus can be kept under surveillance. However, MRC as a non‐invasive imaging modality is a promising alternative to CC in the detection of clinically relevant polyps larger than 5 mm in diameter. J. Magn. Reson. Imaging 2006. © 2006 Wiley‐Liss, Inc.