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Evaluating contrast kinetics by acquiring 2D images during 3D contrast‐enhanced MR angiography
Author(s) -
AlKwifi Osama,
Farb Richard,
Stainsby Jeffrey,
Wright Graham A.
Publication year - 2006
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20647
Subject(s) - contrast (vision) , magnetic resonance angiography , magnetic resonance imaging , angiography , temporal resolution , artifact (error) , signal (programming language) , nuclear medicine , radiology , computer science , nuclear magnetic resonance , biomedical engineering , medicine , artificial intelligence , physics , optics , programming language
Abstract Purpose To monitor contrast kinetics by acquiring multiple 2D images during 3D contrast‐enhanced magnetic resonance angiography (CE MRA). Materials and Methods A 2D real‐time autotriggering tool was integrated into a 3D sequence, enabling it to run multiple times during 3D acquisition. Several dummy scans were applied after each transition to maintain the steady state condition of both sequences. The number of the acquired 2D images and their distribution can be adjusted. Each 2D image was saved along with its associated timing. Contrast signal variations over time were plotted, reflecting selective signal measurement over an artery and vein from the saved 2D images. Results Different contrast kinetics timings were calculated from the resulting plot. Contrast arrival time to the internal cerebral artery was 13.2 ± 1.2 seconds and the peak arterial to peak venous (at the confluence of sinuses) enhancement was 6.7 ± 0.6 seconds. The observed timing could be used for 3D sequence optimization; the saved 2D images are useful in detecting and characterizing vascular abnormalities. Conclusion Integrating 2D and 3D sequences into one sequence to monitor contrast kinetics through the neurovasculature is feasible without the need for extra injections or reduced spatial resolution. The technique can also be used in different parts of the body to extract useful clinical information. J. Magn. Reson. Imaging 2006. © 2006 Wiley‐Liss, Inc.