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Role of functional imaging in neurological disorders
Author(s) -
Weiller Cornelius,
May Arne,
Sach Miriam,
Buhmann Carsten,
Rijntjes Michel
Publication year - 2006
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20591
Subject(s) - neuroimaging , amyotrophic lateral sclerosis , neuroscience , multiple sclerosis , medicine , disease , functional brain imaging , functional imaging , subclinical infection , stroke (engine) , physical medicine and rehabilitation , pathology , psychology , psychiatry , mechanical engineering , engineering
Neuroimaging in recent years has greatly contributed to our understanding of a wide range of aspects related to central neurological diseases. These include the classification and localization of disease, such as in headache; the understanding of pathology, such as in Parkinson's disease (PD); the mechanisms of reorganization, such as in stroke and multiple sclerosis (MS); and the subclinical progress of disease, such as in amyotrophic lateral sclerosis (ALS). Apart from presurgical mapping, however, the clinical applications so far are limited. Nevertheless, functional imaging does enable the formulation of neurobiological hypotheses that can be tested clinically, and thus is well suited for testing classic clinical hypotheses about how the brain works. Understanding the mechanisms and sites of pathology, such as has been achieved in cluster headaches, facilitates the development of new therapeutic strategies. J. Magn. Reson. Imaging 2006. © 2006 Wiley‐Liss, Inc.