Premium
Clinical applicability of functional MRI
Author(s) -
Detre John A.
Publication year - 2006
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20585
Subject(s) - neuroscience , neuroimaging , functional magnetic resonance imaging , modality (human–computer interaction) , psychology , cognitive neuroscience , functional imaging , resting state fmri , cognition , computer science , artificial intelligence
Abstract Functional MRI (fMRI) has become the most widely used modality for examining human brain function in basic and clinical neuroscience. As compared to the application of fMRI in basic neuroscience research, clinical fMRI presents unique challenges. A growing body of literature supports the feasibility of clinical fMRI, with the best‐studied applications being localization of motor cortex and lateralization of language. While it may be tempting to assume that fMRI will supercede prior approaches, it may turn out that fMRI will be used to complement more difficult or invasive methods rather than replace them entirely. This article focuses on fMRI studies in patients and patient populations. Specific considerations for such applications include pathophysiological effects on functional physiology, brain–behavior correlations in the presence of cognitive or sensorimotor deficits, and test‐retest reliability for longitudinal studies. J. Magn. Reson. Imaging 2006. © 2006 Wiley‐Liss, Inc.