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Myocardial tagging and strain analysis at 3 Tesla: Comparison with 1.5 Tesla imaging
Author(s) -
Valeti V. Uma,
Chun Wookjin,
Potter Donald D.,
Araoz Philip A.,
McGee Kiaran P.,
Glockner James F.,
Christian Timothy F.
Publication year - 2006
Publication title -
journal of magnetic resonance imaging
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.563
H-Index - 160
eISSN - 1522-2586
pISSN - 1053-1807
DOI - 10.1002/jmri.20527
Subject(s) - cardiac cycle , contrast to noise ratio , systole , nuclear medicine , strain (injury) , medicine , diastole , nuclear magnetic resonance , physics , cardiology , anatomy , image quality , artificial intelligence , computer science , blood pressure , image (mathematics)
Abstract Purpose To determine whether imaging at 3 T could improve and prolong the tag contrast compared to images acquired at 1.5 T in normal volunteers, and whether such improvement would translate into the ability to perform strain measurements in diastole. Materials and Methods Normal volunteers ( N = 13) were scanned at 1.5 T (GE Signa CV/i) and 3.0 T (GE VH/i). An ECG‐triggered, segmented k‐space, spoiled‐gradient‐echo grid‐tagged sequence was used during cine acquisition. Tag contrast was determined by the difference of the mean signal intensity (SI) of the tagline to the mean SI of the myocardium divided by the standard deviation (SD) of the noise (CNR tag ). Matched short‐axis (SA) slices were analyzed. Strain measurements were performed on images using a 2D strain analysis software program (harmonic phase (HARP)). Results The average CNR tag over the cardiac cycle was superior at 3 T compared to 1.5 T for all slices (3 T: 23.4 ± 12.1, 1.5 T: 9.8 ± 8.4; P < 0.0001). This difference remained significant at cycle initiation, end‐systole, and the end R‐R interval (at cycle termination: 3 T = 14.0 ± 11.0 vs. 1.5 T = 4.4 ± 3.5; P < 0.01). Strain measures were obtainable only in early systole for 1.5 T images, but were robust throughout the entire R‐R interval for 3 T images. Conclusion Imaging at 3 T had a significant benefit for myocardial tag persistence through the cardiac cycle. The improvement allowed strain analysis to be performed into diastole. J. Magn. Reson. Imaging 2006. © 2006 Wiley‐Liss, Inc.

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